Diseases
Diseases are monster afflictions: an encounter can stamp a disease onto the monsters it spawns, and their hits have a chance to infect you.
How Diseases Hurt You
Every disease deals flat damage on a tick — so much health every so often, for its duration. Elemental resistances do not reduce it. On top of the tick, two families punish specific actions:
- Aetherflux-family diseases also damage you **every time you
move** — when you catch one, stand still until it passes.
- Radiance also damages you every time you attack — ease off
until it clears.
Stacking diseases (Sporeblight and its kin) refresh and extend as you keep getting hit — break away from the pack before they pile up. Diseases applied by a boss's melee hits tick roughly 40% harder than the same disease from an ordinary monster.
Cleansing by Element
The six elements oppose in pairs: Fire↔Water, Air↔Earth, Holy↔Dark. Taking a hit from a monster whose attack carries the element opposing a disease you have cleanses that disease. A frost-bearing attack burns Cindercurse off you; a flame washes Frostbite away. Fighting the right monsters can scrub you clean.
All 32 Diseases
| ID | Disease | Tick | ID | Disease | Tick |
|---|---|---|---|---|---|
| 1 | Sporeblight | 18 / 1s, 8s | 17 | Scorchmark | 30 / 0.5s, 4s |
| 2 | Cindercurse | 35 / 0.5s, 5s | 18 | Ironrot | 8 / 2s, 10s |
| 3 | Sunscourge | 10 / 2s, 8s | 19 | Stormfrazzle | 16 / 1s, 6s |
| 4 | Voltsurge | 12 / 0.8s, 6s | 20 | Crushed | 10 / 1s, 5s |
| 5 | Stonebind | see note | 21 | Flashfever | 20 / 0.5s, 4s |
| 6 | Frostblight | 136 / 2s, 8s | 22 | Disoriented | 6 / 1s, 4s |
| 7 | Aetherflux | 22 / 1s + on move, 7s | 23 | Voidcling | 15 / 1s, 8s |
| 8 | Radiance | 15 / 1s + on attack, 6s | 24 | Crystalbleed | 20 / 1s, 6s |
| 9 | Voidtouched | 12 / 1s, 10s | 25 | Boneweave | 10 / 1.5s, 8s |
| 10 | Sporeblight (Boss) | 28 / 0.8s, 10s | 26 | Roothold | 10 / 1s, 4s |
| 11 | Cindercurse (Boss) | 45 / 0.5s, 6s | 27 | Ashveil | 8 / 2s, 7s |
| 12 | Aetherflux (Boss) | 30 / 0.8s + on move, 8s | 28 | Thunderfaint | 14 / 1s, 4s |
| 13 | Burning Wound | 22 / 1s, 6s | 29 | Petrify | 6 / 1s, 5s |
| 14 | Drenched | 5 / 2s, 8s | 30 | Corrosion | 12 / 1s, 10s |
| 15 | Dustlung | see note | 31 | Frostbite | see note |
| 16 | Galechill | 10 / 1s, 5s | 32 | Hexweave | 14 / 1.5s, 8s |
Note: Stonebind, Dustlung, and Frostbite currently deal no damage — their stored-damage mechanic is dormant in the live tuning. Treat them as a warning of what the encounter can throw at you rather than a threat in themselves.
Three diseases have stronger boss variants (IDs 10–12), tuned for boss encounters.
Diseases vs Affixes
They're separate systems: diseases afflict you in combat; affixes are item prefixes and equipment set bonuses. An encounter can use one disease for its monsters while dropping loot from a different affix group.